Travelling by bus is often the quickest and most direct way to get from one Czech town to another. It is also sometimes the only way (unless you travel by car) because some Czech villages are not serviced by trains, or their train stations are far enough from the residential areas to make the bus a better option. Bus terminals are mostly located near the city centre to be better accessible by foot, often close to the main railway station.
If you intend on driving, realise that a license acquired in all E.U. countries is valid throughout the E.U., but any driver from a non E.U. country needs to obtain a driver’s license for the Czech Rep if they’re residing, for the long-term, in the country. This is also true if they possess a car bought in the Czech Rep. An insurance certificate is also needed.
Most parts of central Prague have meter zones with fees from 30 CZK to 120 CZK per hour (or you can arrange a long-term parking permit). There are some car parks close to metro stations plus underground car parks. To reduce congestion in the city, Park&Ride parking places are used on the outskirts of Prague.
Although Prague isn’t as accessible for those with special needs as many other cities, the facilities are slowly improving. Things are made tough for those in wheelchairs by the many narrow streets covered in uneven paving found here, but ramps are being constructed on many buildings to increase the ease of access. Hotels and public transport are also increasing their accessibility for those with special needs, although only a minority of restaurants are wheelchair friendly in the city.