在欧洲大多数的城市，夜生活方面当然不可少的是酒吧、夜店，而布拉格也是如此。要逐一列出著名酒吧或夜店是件难事，因为这些娱乐场所的名气更跌相当快速，今日的红星，可能就在竞争下牺牲了。
在旅馆或是青年旅社中，可以找到这方面信息的杂志，其中列出这些场所举办的活动，以及布拉格最精采的夜生活所在地。某些有趣的地方，更是值得一探的，有些还是名气屹立不摇的酒吧。酒吧是从日间就开始营业，夜店则是晚上十一点以后，营业至凌晨四点。如果您到这个时候还是意犹未尽，还是可以在市区找到仍旧营业的夜店。
Duplex – Duplex is one of Prague’s most popular nightclubs with huge dance halls filled with local teenagers and even stag-party stragglers. It is a combination of nightclub, café and restaurant. During the day the 6th-floor terrace restaurant is a great place for coffee to enjoy the views. At night offers a view overlooking the lights of Wenceslas Square.
Location: Wenceslas Square 21, New Town, www.duplex.cz
Mecca - very fashionable club, featuring industrial-chic club to dance to house and techno music.
Location: Pruhonu 3, Holesovice, www.mecca.cz
Karlovy Lazne – another huge and very cool night club. Each floor has its own style, from chill out to hard core trance; live bands at ground level, dance to classic disco on first floor (Discotheque), rock to 1960s and 70s music on the second floor (Kaleidoskop), or house and techno on the third floor (Paradogs).
Location: Novotneho lavka, Old Town (close to Charles Bridge), www.karlovylazne.cz
RadostFX – this very famous club features top local and international DJs. Exquisite sofas, mosaic-topped tables … Café serving great veggie food and cheesecakes, a Moroccan lounge in the back for relaxation and downstairs dance club that only gets going after late hours.
Locaton: Belehradska 120,Vinohrady (close to underground station IP Pavlova), www.radostfx.cz
La Fabrique – disco with a couple of dance floors for people of all ages.
Location: Uhelný trh 2, Old Town, www.lafabrique.cz
Roxy – If funk and techno is your favourite then Roxy is the best club in town. Arrive around midnight when the fun starts.
Location: Dlouhá 33, metro Namesti Republiky, www.roxy.cz
